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"type": "Note",
"summary": "Biomanufacturing and Science Research",
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"published": "2022-11-10T03:53:52Z",
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"content": "<p>I spent a very valuable hour tonight talking on the phone with a good friend in <a href=\"https://qoto.org/tags/Biomanufacturing\" class=\"mention hashtag\" rel=\"tag\">#<span>Biomanufacturing</span></a>. Her research is in <a href=\"https://qoto.org/tags/Upstream\" class=\"mention hashtag\" rel=\"tag\">#<span>Upstream</span></a> process development for fancy <a href=\"https://qoto.org/tags/AAV\" class=\"mention hashtag\" rel=\"tag\">#<span>AAV</span></a> <a href=\"https://qoto.org/tags/GeneTherapy\" class=\"mention hashtag\" rel=\"tag\">#<span>GeneTherapy</span></a> stuff. Her work is all very much "If we figure this out it will massively change the lives of millions of people someday! Unless it doesn't work and my research ends up as a footnote..."</p><p>BUT WAIT...most good <a href=\"https://qoto.org/tags/Science\" class=\"mention hashtag\" rel=\"tag\">#<span>Science</span></a> is built on footnotes! Footnotes are actually the bones of the researchers who found out their ideas didn't work. They did it right, but they were wrong. Most science is TOTALLY the future. Right up until the moment it's NOT... </p><p>It's important to remember that none of the people in footnotes were failures.</p><p>Long ago I did frontier research and I know the rewards of that life. I also know the feeling of seeing data from the international community CRUSH YOU because your paradigm was proven false. That's life in science. No one figures anything out alone.</p><p>In contrast to my friend, my work is as a <a href=\"https://qoto.org/tags/GMP\" class=\"mention hashtag\" rel=\"tag\">#<span>GMP</span></a> <a href=\"https://qoto.org/tags/Downstream\" class=\"mention hashtag\" rel=\"tag\">#<span>Downstream</span></a> <a href=\"https://qoto.org/tags/QualityControl\" class=\"mention hashtag\" rel=\"tag\">#<span>QualityControl</span></a> analyst in <a href=\"https://qoto.org/tags/Biomanufacturing\" class=\"mention hashtag\" rel=\"tag\">#<span>Biomanufacturing</span></a>. My job is to make sure we make the known science work. We make it work EVERY TIME.</p><p>I'm results-focused because the comparatively mundane <a href=\"https://qoto.org/tags/biotherapeutics\" class=\"mention hashtag\" rel=\"tag\">#<span>biotherapeutics</span></a> I help produce go in patients every day. Therapeutic <a href=\"https://qoto.org/tags/Proteins\" class=\"mention hashtag\" rel=\"tag\">#<span>Proteins</span></a> like the ones that combat <a href=\"https://qoto.org/tags/Autoimmune\" class=\"mention hashtag\" rel=\"tag\">#<span>Autoimmune</span></a> <a href=\"https://qoto.org/tags/Disease\" class=\"mention hashtag\" rel=\"tag\">#<span>Disease</span></a> are a massive benefit to society. I didn't develop any of these therapies but I make sure no one dies because of a mistake at the factory.</p><p>So I don't push any boundaries as a scientist. I very much make sure to NEVER push boundaries. NEVER EVER. Pushing boundaries is a problem. I'm here to execute.</p><p>So all I can leave you with is this: Is science a series of questions, or a series of answers?</p><p>What do we really need more? I've always struggled with this. I still don't know.</p><p>If you're honest and remember reading Kuhn, you know science has never proven anything. But wow we've had some results.</p><p>Go out.<br />Never settle.<br />Demand results.</p>",
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"en": "<p>I spent a very valuable hour tonight talking on the phone with a good friend in <a href=\"https://qoto.org/tags/Biomanufacturing\" class=\"mention hashtag\" rel=\"tag\">#<span>Biomanufacturing</span></a>. Her research is in <a href=\"https://qoto.org/tags/Upstream\" class=\"mention hashtag\" rel=\"tag\">#<span>Upstream</span></a> process development for fancy <a href=\"https://qoto.org/tags/AAV\" class=\"mention hashtag\" rel=\"tag\">#<span>AAV</span></a> <a href=\"https://qoto.org/tags/GeneTherapy\" class=\"mention hashtag\" rel=\"tag\">#<span>GeneTherapy</span></a> stuff. Her work is all very much "If we figure this out it will massively change the lives of millions of people someday! Unless it doesn't work and my research ends up as a footnote..."</p><p>BUT WAIT...most good <a href=\"https://qoto.org/tags/Science\" class=\"mention hashtag\" rel=\"tag\">#<span>Science</span></a> is built on footnotes! Footnotes are actually the bones of the researchers who found out their ideas didn't work. They did it right, but they were wrong. Most science is TOTALLY the future. Right up until the moment it's NOT... </p><p>It's important to remember that none of the people in footnotes were failures.</p><p>Long ago I did frontier research and I know the rewards of that life. I also know the feeling of seeing data from the international community CRUSH YOU because your paradigm was proven false. That's life in science. No one figures anything out alone.</p><p>In contrast to my friend, my work is as a <a href=\"https://qoto.org/tags/GMP\" class=\"mention hashtag\" rel=\"tag\">#<span>GMP</span></a> <a href=\"https://qoto.org/tags/Downstream\" class=\"mention hashtag\" rel=\"tag\">#<span>Downstream</span></a> <a href=\"https://qoto.org/tags/QualityControl\" class=\"mention hashtag\" rel=\"tag\">#<span>QualityControl</span></a> analyst in <a href=\"https://qoto.org/tags/Biomanufacturing\" class=\"mention hashtag\" rel=\"tag\">#<span>Biomanufacturing</span></a>. My job is to make sure we make the known science work. We make it work EVERY TIME.</p><p>I'm results-focused because the comparatively mundane <a href=\"https://qoto.org/tags/biotherapeutics\" class=\"mention hashtag\" rel=\"tag\">#<span>biotherapeutics</span></a> I help produce go in patients every day. Therapeutic <a href=\"https://qoto.org/tags/Proteins\" class=\"mention hashtag\" rel=\"tag\">#<span>Proteins</span></a> like the ones that combat <a href=\"https://qoto.org/tags/Autoimmune\" class=\"mention hashtag\" rel=\"tag\">#<span>Autoimmune</span></a> <a href=\"https://qoto.org/tags/Disease\" class=\"mention hashtag\" rel=\"tag\">#<span>Disease</span></a> are a massive benefit to society. I didn't develop any of these therapies but I make sure no one dies because of a mistake at the factory.</p><p>So I don't push any boundaries as a scientist. I very much make sure to NEVER push boundaries. NEVER EVER. Pushing boundaries is a problem. I'm here to execute.</p><p>So all I can leave you with is this: Is science a series of questions, or a series of answers?</p><p>What do we really need more? I've always struggled with this. I still don't know.</p><p>If you're honest and remember reading Kuhn, you know science has never proven anything. But wow we've had some results.</p><p>Go out.<br />Never settle.<br />Demand results.</p>"
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