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to the server to view the underlying object.
{
"@context": [
"https://www.w3.org/ns/activitystreams",
{
"ostatus": "http://ostatus.org#",
"atomUri": "ostatus:atomUri",
"inReplyToAtomUri": "ostatus:inReplyToAtomUri",
"conversation": "ostatus:conversation",
"sensitive": "as:sensitive",
"toot": "http://joinmastodon.org/ns#",
"votersCount": "toot:votersCount",
"expiry": "toot:expiry",
"Hashtag": "as:Hashtag"
}
],
"id": "https://qoto.org/users/cyrilpedia/statuses/111414757858001415",
"type": "Note",
"summary": null,
"inReplyTo": null,
"published": "2023-11-15T13:18:08Z",
"url": "https://qoto.org/@cyrilpedia/111414757858001415",
"attributedTo": "https://qoto.org/users/cyrilpedia",
"to": [
"https://www.w3.org/ns/activitystreams#Public"
],
"cc": [
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],
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"conversation": "tag:qoto.org,2023-11-15:objectId=111414757857959909:objectType=Conversation",
"context": "https://qoto.org/contexts/111414757857959909",
"content": "<p>"Although type 1 conventional dendritic cells (cDC1s) were not required for initial priming of CD4+ T cells, cDC1s were required for CD4+ T cell expansion and gut homing. cDC1s were also a major source of IL-12 that was not required for priming but promoted full differentiation of CD4+ T cells and local production of IFN-γ. Together, these studies reveal distinct roles for cDC1s in shaping CD4+ T cell responses to enteric infection: first to drive early expansion in the mesLN and second to drive effector responses in the gut."<br /><a href=\"https://qoto.org/tags/InfectionImmunity\" class=\"mention hashtag\" rel=\"tag\">#<span>InfectionImmunity</span></a> <a href=\"https://qoto.org/tags/Immunology\" class=\"mention hashtag\" rel=\"tag\">#<span>Immunology</span></a> <a href=\"https://qoto.org/tags/MucosalImmunology\" class=\"mention hashtag\" rel=\"tag\">#<span>MucosalImmunology</span></a> <a href=\"https://qoto.org/tags/parasitology\" class=\"mention hashtag\" rel=\"tag\">#<span>parasitology</span></a> <a href=\"https://qoto.org/tags/Preprint\" class=\"mention hashtag\" rel=\"tag\">#<span>Preprint</span></a></p><p><a href=\"https://www.biorxiv.org/content/10.1101/2023.11.11.566669v1\" target=\"_blank\" rel=\"nofollow noopener noreferrer\"><span class=\"invisible\">https://www.</span><span class=\"ellipsis\">biorxiv.org/content/10.1101/20</span><span class=\"invisible\">23.11.11.566669v1</span></a></p>",
"contentMap": {
"en": "<p>"Although type 1 conventional dendritic cells (cDC1s) were not required for initial priming of CD4+ T cells, cDC1s were required for CD4+ T cell expansion and gut homing. cDC1s were also a major source of IL-12 that was not required for priming but promoted full differentiation of CD4+ T cells and local production of IFN-γ. Together, these studies reveal distinct roles for cDC1s in shaping CD4+ T cell responses to enteric infection: first to drive early expansion in the mesLN and second to drive effector responses in the gut."<br /><a href=\"https://qoto.org/tags/InfectionImmunity\" class=\"mention hashtag\" rel=\"tag\">#<span>InfectionImmunity</span></a> <a href=\"https://qoto.org/tags/Immunology\" class=\"mention hashtag\" rel=\"tag\">#<span>Immunology</span></a> <a href=\"https://qoto.org/tags/MucosalImmunology\" class=\"mention hashtag\" rel=\"tag\">#<span>MucosalImmunology</span></a> <a href=\"https://qoto.org/tags/parasitology\" class=\"mention hashtag\" rel=\"tag\">#<span>parasitology</span></a> <a href=\"https://qoto.org/tags/Preprint\" class=\"mention hashtag\" rel=\"tag\">#<span>Preprint</span></a></p><p><a href=\"https://www.biorxiv.org/content/10.1101/2023.11.11.566669v1\" target=\"_blank\" rel=\"nofollow noopener noreferrer\"><span class=\"invisible\">https://www.</span><span class=\"ellipsis\">biorxiv.org/content/10.1101/20</span><span class=\"invisible\">23.11.11.566669v1</span></a></p>"
},
"attachment": [],
"tag": [
{
"type": "Hashtag",
"href": "https://qoto.org/tags/InfectionImmunity",
"name": "#InfectionImmunity"
},
{
"type": "Hashtag",
"href": "https://qoto.org/tags/MucosalImmunology",
"name": "#MucosalImmunology"
},
{
"type": "Hashtag",
"href": "https://qoto.org/tags/immunology",
"name": "#immunology"
},
{
"type": "Hashtag",
"href": "https://qoto.org/tags/parasitology",
"name": "#parasitology"
},
{
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"href": "https://qoto.org/tags/preprint",
"name": "#preprint"
}
],
"replies": {
"id": "https://qoto.org/users/cyrilpedia/statuses/111414757858001415/replies",
"type": "Collection",
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"partOf": "https://qoto.org/users/cyrilpedia/statuses/111414757858001415/replies",
"items": []
}
}
}