A small tool to view real-world ActivityPub objects as JSON! Enter a URL
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Accept
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to the server to view the underlying object.
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"sensitive": "as:sensitive",
"toot": "http://joinmastodon.org/ns#",
"votersCount": "toot:votersCount"
}
],
"id": "https://c.im/users/cdarwin/statuses/113534713903587142",
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"published": "2024-11-23T22:50:50Z",
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"content": "<p>Previous research has shown rilmenidine mimics the effects of caloric restriction on a cellular level. Reducing available energy while maintaining nutrition within the body has been shown to extend lifespans in several animal models.</p><p>Whether this translates to human biology, or is a potential risk to our health, is a topic of ongoing debate. Finding ways to achieve the same benefits without the costs of extreme calorie cutting could lead to new ways to improve health in old age.</p><p>In a study published in 2023, young and old Caenorhabditis elegans worms treated with the drug – which is normally used to treat high blood pressure – lived longer and presented higher measures in a variety of health markers in the same way as restricting calories, as the scientists had hoped.</p><p>"For the first time, we have been able to show in animals that rilmenidine can increase lifespan," said molecular biogerontologist João Pedro Magalhães, from the University of Birmingham in the UK.</p><p>"We are now keen to explore if rilmenidine may have other clinical applications."<br /><a href=\"https://www.sciencealert.com/a-common-blood-pressure-drug-extends-lifespan-and-slows-aging-in-animals\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" translate=\"no\"><span class=\"invisible\">https://www.</span><span class=\"ellipsis\">sciencealert.com/a-common-bloo</span><span class=\"invisible\">d-pressure-drug-extends-lifespan-and-slows-aging-in-animals</span></a></p>",
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"en": "<p>Previous research has shown rilmenidine mimics the effects of caloric restriction on a cellular level. Reducing available energy while maintaining nutrition within the body has been shown to extend lifespans in several animal models.</p><p>Whether this translates to human biology, or is a potential risk to our health, is a topic of ongoing debate. Finding ways to achieve the same benefits without the costs of extreme calorie cutting could lead to new ways to improve health in old age.</p><p>In a study published in 2023, young and old Caenorhabditis elegans worms treated with the drug – which is normally used to treat high blood pressure – lived longer and presented higher measures in a variety of health markers in the same way as restricting calories, as the scientists had hoped.</p><p>"For the first time, we have been able to show in animals that rilmenidine can increase lifespan," said molecular biogerontologist João Pedro Magalhães, from the University of Birmingham in the UK.</p><p>"We are now keen to explore if rilmenidine may have other clinical applications."<br /><a href=\"https://www.sciencealert.com/a-common-blood-pressure-drug-extends-lifespan-and-slows-aging-in-animals\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" translate=\"no\"><span class=\"invisible\">https://www.</span><span class=\"ellipsis\">sciencealert.com/a-common-bloo</span><span class=\"invisible\">d-pressure-drug-extends-lifespan-and-slows-aging-in-animals</span></a></p>"
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